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I reforged gear without haste to have haste (from crit) and reforged all gear with haste to have mastery(from crit). So far I am really enjoying the results for mutilate, and the results for sub aren't too bad either.
For mutilate I find that mastery really emphasizes envenom uptime. The closer you get to 100% uptime, the more benefit mastery will have. This also means using envenom to get DP stacked up quickly on a target switch (i.e. envenom before switching to slimes on putricide).
For Subtlety it's obvious that mastery is less effective because you use two finishers without damage, but I pulled 10k dps on Toravon 25 last night and I'm still having issues keeping track of everything. Once I get the buff management down I think I'll be pulling even better numbers. I plan to do more subt testing tonight in ICC25. I still think this spec has too many buttons, and it's obvious that a player who can manage all the cooldowns and finishers can really dominate.