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Some quick sims show that the difference is extremely minimal (4 dps loss switching to 2/3 Morbidity in my gear). Runic power mastery would give you a lot more leeway with dumping RP, but wouldn't benefit you on most tank/spank fights.
In any case, the difference in DPS from switching those points around is extremely minimal, and can be safely switched around for personal preference.
Ok, that's very good to know. Appreciate it.